The average bus between Lucerne and Orio al Serio takes 5h 25m and the fastest bus takes 5h 10m. The bus service runs several times per day from Lucerne to Orio al Serio. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Lucerne and Orio al Serio. The earliest departure is at 5:15 AM in the morning, and the last departure from Lucerne is at 11:30 PM which arrives into Orio al Serio at 7:00 AM. All services require a transfer, and take on average 5h 25m. The schedules shown below are for the next available departures.

7h 35m • 1 change

7h 10m • 1 change
Arrives next day

7h 30m • 1 change

7h 35m • 1 change

7h 10m • 1 change
Arrives next day

7h 30m • 1 change

7h 35m • 1 change

7h 10m • 1 change
Arrives next day

7h 30m • 1 change
Want to know about travelling from Lucerne to Orio al Serio? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lucerne to Orio al Serio. However, there are services departing from Lucerne station and arriving at Orio al Serio station via Milan. The journey, including transfers, takes approximately 5h 25m.
Lucerne to Orio al Serio bus services, operated by FlixBus, depart from Luzern station.
Lucerne to Orio al Serio bus services, operated by FlixBus, arrive at Bergamo station.
Book your Lucerne to Orio al Serio bus tickets online with FlixBus, BlaBlaCar Bus and RegioJet.
The distance between Lucerne and Orio al Serio is 186.2 km. The road distance is 295 km.
You can take a bus from Luzern to Bergamo via Milano, Autostazione Lampugnano in around 4h 46m.