Lugano to Mesenzana Buses

Trip Overview

The average bus between Lugano and Mesenzana takes 2h 4m and the fastest bus takes 1h 7m. There is a bus service every few hours from Lugano to Mesenzana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2h 4m
Duration: 27 km
Distance: Hourly
Frequency

Bus, line 429 bus

best

Take the bus from Agno, Stazione to Ponte Tresa, Stazionebus Ev
Take the bus from Ponte Tresa, Stazione to Luino, Stazione FSbus 429
Take the bus from Luino, Marconi,Stazione FS to Mesenzana, Provinciale fr. bv Malpensatabus

1h 48m

Lugano to Mesenzana bus times

Buses run hourly between Lugano and Mesenzana. The earliest departure is at 12:26 AM at night, and the last departure from Lugano is at 11:56 PM which arrives into Mesenzana at 5:52 AM. All services require a transfer at Ponte Tresa, Stazione and take an average of 2h 4m. The schedules shown below are for the next available departures.

Departing Thursday, October 29, 2026

11:56 PM → 5:52 AM
Arrives next day
5h 56m • 2 changes

Departing Friday, October 30, 2026

12:26 AM → 6:43 AM
6h 17m • 2 changes
6:11 AM → 7:38 AM
1h 27m • 2 changes
6:56 AM → 8:13 AM
1h 17m • 2 changes
7:26 AM → 8:38 AM
1h 12m • 2 changes
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Departing Saturday, October 31, 2026

1:46 AM → 6:43 AM
4h 57m • 2 changes
5:41 AM → 7:38 AM
1h 57m • 2 changes
6:56 AM → 8:38 AM
1h 42m • 2 changes
7:56 AM → 9:03 AM
1h 7m • 2 changes
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Departing Sunday, November 1, 2026

6:56 AM → 8:38 AM
1h 42m • 2 changes
7:56 AM → 9:38 AM
1h 42m • 2 changes
11:26 AM → 1:38 PM
2h 12m • 2 changes
12:26 PM → 2:38 PM
2h 12m • 2 changes
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Departing Monday, November 2, 2026

12:26 AM → 6:35 AM
6h 9m • 2 changes
5:41 AM → 7:05 AM
1h 24m • 2 changes
6:11 AM → 7:38 AM
1h 27m • 2 changes
7:26 AM → 8:38 AM
1h 12m • 2 changes
Show more

Departing Tuesday, November 3, 2026

12:26 AM → 6:43 AM
6h 17m • 2 changes
6:11 AM → 7:38 AM
1h 27m • 2 changes
6:56 AM → 8:13 AM
1h 17m • 2 changes
7:26 AM → 8:38 AM
1h 12m • 2 changes
Show more

Departing Wednesday, November 4, 2026

12:26 AM → 6:43 AM
6h 17m • 2 changes
6:11 AM → 7:38 AM
1h 27m • 2 changes
6:56 AM → 8:13 AM
1h 17m • 2 changes
7:26 AM → 8:38 AM
1h 12m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Lugano to Mesenzana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.