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Luton to Manchester Piccadilly Station buses

Find Transport to Manchester Piccadilly Station

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Trip Overview

The average bus between Luton and Manchester Piccadilly Station takes 4h 30m and the fastest bus takes 3h 30m. There is a bus service every few hours from Luton to Manchester Piccadilly Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

4h 30m
Duration
173 mi
Distance
£30
Average price
Hourly
Frequency

Bus via Milton Keynes Coachway

best
  1. Take the bus from Milton Keynes Coachway to Manchester Central Coach Stationbus bus 541 / ...
5h 28m
£25–45

Luton to Manchester Piccadilly Station bus times

Buses run hourly between Luton and Manchester Piccadilly Station. The earliest departure is at 12:05 AM at night, and the last departure from Luton is at 10:45 PM which arrives into Manchester Piccadilly Station at 2:15 AM. All services require a transfer at Milton Keynes Coachway and take an average of 4h 30m. The schedules shown below are for the next available departures.

Departing Sunday, October 11, 2026

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    National ExpressNational Express4h 35m • 1 change

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    National ExpressNational Express4h 35m • 1 change

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    National ExpressNational Express4h 25m • 1 change

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    National ExpressNational Express3h 50m • 1 change
  • Show more

Departing Monday, October 12, 2026

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    National ExpressNational Express6h 10m • 1 change

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    National ExpressNational Express4h 35m • 1 change

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    National ExpressNational Express4h 10m • 1 change

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    National ExpressNational Express4h 5m • 1 change
  • Show more

Departing Tuesday, October 13, 2026

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    National ExpressNational Express6h 10m • 1 change

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    National ExpressNational Express4h 35m • 1 change

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    National ExpressNational Express4h 10m • 1 change

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    National ExpressNational Express4h 5m • 1 change
  • Show more

Departing Wednesday, October 14, 2026

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    National ExpressNational Express6h 10m • 1 change

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    National ExpressNational Express4h 35m • 1 change

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    National ExpressNational Express4h 10m • 1 change

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    National ExpressNational Express4h 5m • 1 change
  • Show more

Departing Thursday, October 15, 2026

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    National ExpressNational Express6h 10m • 1 change

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    National ExpressNational Express4h 35m • 1 change

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    National ExpressNational Express4h 10m • 1 change

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    National ExpressNational Express4h 5m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Luton to Manchester Piccadilly Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Luton to Manchester Piccadilly Station.ExpandLaunch map view
  • Distance: 172.9 mi
  • Duration: 4h 30m

What companies run services between Luton, England and Manchester Piccadilly Station, England?

National Express operates a bus from Milton Keynes Coachway to Manchester Central Coach Station hourly. Tickets cost £22–40 and the journey takes 3h 55m.

Operators