The average bus between Luton and Middlesbrough takes 6h 58m and the fastest bus takes 5h 10m. The bus service runs several times per day from Luton to Middlesbrough. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Luton and Middlesbrough. The earliest departure is at 3:00 AM at night, and the last departure from Luton is at 10:45 PM which arrives into Middlesbrough at 3:55 AM. All services require a transfer, and take on average 6h 58m. The schedules shown below are for the next available departures.

9h 55m • 1 change

5h 25m • 1 change
Arrives next day

5h 10m • 1 change

9h 55m • 1 change

5h 25m • 1 change
Arrives next day

5h 10m • 1 change

9h 55m • 1 change

5h 25m • 1 change
Arrives next day

5h 10m • 1 change

9h 55m • 1 change

5h 25m • 1 change
Arrives next day

5h 10m • 1 change
Want to know about travelling from Luton to Middlesbrough? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Luton to Middlesbrough. However, there are services departing from Luton station and arriving at Middlesbrough station via Bus Station Stand Z station. The journey, including transfers, takes approximately 6h 58m.
Luton to Middlesbrough bus services, operated by National Express, depart from Milton Keynes Coachway station.
Luton to Middlesbrough bus services, operated by National Express, arrive at Bus Station Stand Z.
Book your Luton to Middlesbrough bus tickets online with National Express.
The distance between Luton and Middlesbrough is 304.7 km. The road distance is 353 km.
National Express operates a bus from Milton Keynes Coachway to Bus Station Stand Z every 4 hours. Tickets cost £35–90 and the journey takes 4h 20m.