Lyon to Avignon Centre Buses

Lyon to Avignon Centre buses

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Trip Overview

The average bus between Lyon and Avignon Centre takes 3h 44m and the fastest bus takes 3h. The bus service runs several times per day from Lyon to Avignon Centre. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 44m
Duration: 231 km
Distance: €24
Average price: Every 3 hours
Frequency

Bus

best

Take the bus from Lyon to Avignonbus FlixBus N1135 / ...

3h 7m

€19–35

Lyon to Avignon Centre bus times

Buses run every 3 hours between Lyon and Avignon Centre. The earliest departure is at 2:35 AM at night, and the last departure from Lyon is at 11:50 PM which arrives into Avignon Centre at 6:05 AM. All services require a transfer, and take on average 3h 44m. The schedules shown below are for the next available departures.

Departing Friday, September 4, 2026

5:35 PM → 9:20 PM
3h 45m • 1 change
11:50 PM → 6:03 AM
Arrives next day
6h 13m • 1 change

Departing Saturday, September 5, 2026

2:35 AM → 7:35 AM
5h • 1 change
4:40 AM → 8:05 AM
3h 25m • 1 change
5:20 AM → 8:21 AM
3h 1m • 1 change
8:30 AM → 11:41 AM
3h 11m • 1 change
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Departing Sunday, September 6, 2026

2:35 AM → 7:49 AM
5h 14m • 1 change
5:20 AM → 8:21 AM
3h 1m • 1 change
8:30 AM → 11:51 AM
3h 21m • 1 change
9:30 AM → 1:23 PM
3h 53m • 1 change
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Departing Monday, September 7, 2026

2:35 AM → 7:46 AM
5h 11m • 1 change
4:40 AM → 8:06 AM
3h 26m • 1 change
5:20 AM → 8:26 AM
3h 6m • 1 change
8:30 AM → 11:37 AM
3h 7m • 1 change
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Departing Tuesday, September 8, 2026

2:35 AM → 7:46 AM
5h 11m • 1 change
4:40 AM → 8:06 AM
3h 26m • 1 change
5:20 AM → 8:26 AM
3h 6m • 1 change
8:30 AM → 11:37 AM
3h 7m • 1 change
Show more

Departing Wednesday, September 9, 2026

2:35 AM → 7:46 AM
5h 11m • 1 change
4:40 AM → 8:06 AM
3h 26m • 1 change
5:20 AM → 8:26 AM
3h 6m • 1 change
8:30 AM → 11:37 AM
3h 7m • 1 change
Show more

Departing Thursday, September 10, 2026

2:35 AM → 7:46 AM
5h 11m • 1 change
4:40 AM → 8:06 AM
3h 26m • 1 change
5:20 AM → 8:26 AM
3h 6m • 1 change
8:30 AM → 11:37 AM
3h 7m • 1 change
Show more

Frequently asked questions

Want to know about travelling from Lyon to Avignon Centre? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.