The average bus between Lyon and Gare de Strasbourg takes 7h 6m and the fastest bus takes 6h 39m. The bus service runs several times per day from Lyon to Gare de Strasbourg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Lyon and Gare de Strasbourg. The earliest departure is at 2:05 AM at night, and the last departure from Lyon is at 10:00 PM which arrives into Gare de Strasbourg at 5:22 AM. All services require a transfer at Strasbourg and take an average of 7h 6m. The schedules shown below are for the next available departures.

7h 12m • 1 change
6h 52m • 1 change
7h 12m • 1 change
6h 42m • 1 change
7h 8m • 1 change
6h 59m • 1 change
7h 12m • 1 change
6h 40m • 1 change
7h 8m • 1 change
6h 59m • 1 change
7h 12m • 1 changeArrives next day

7h 32m • 1 changeWant to know about travelling from Lyon to Gare de Strasbourg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Gare de Strasbourg. However, there are services departing from Lyon station and arriving at Strasbourg station via Strasbourg station. The journey, including transfers, takes approximately 7h 6m.
Lyon to Gare de Strasbourg bus services, operated by FlixBus, depart from Lyon station.
Lyon to Gare de Strasbourg bus services, operated by FlixBus, arrive at Strasbourg station.
The distance between Lyon and Gare de Strasbourg is 383.5 km. The road distance is 455 km.
FlixBus operates a bus from Lyon to Strasbourg every 4 hours. Tickets cost €40–65 and the journey takes 6h 40m. BlaBlaCar Bus also services this route 5 times a day.