The average bus between Lyon and Gare de Strasbourg takes 7h 23m and the fastest bus takes 6h 52m. The bus service runs several times per day from Lyon to Gare de Strasbourg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Lyon and Gare de Strasbourg. The earliest departure is at 1:10 AM at night, and the last departure from Lyon is at 10:00 PM which arrives into Gare de Strasbourg at 5:01 AM. All services require a transfer at Strasbourg - L'Étoile Park Bus Station and take an average of 7h 23m. The schedules shown below are for the next available departures.

6h 59m • 1 change
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6h 52m • 1 change
7h 12m • 1 change
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7h 12m • 1 change
6h 59m • 1 change
7h 8m • 1 change
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7h 12m • 1 changeArrives next day

7h 32m • 1 changeWant to know about travelling from Lyon to Gare de Strasbourg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Gare de Strasbourg. However, there are services departing from Lyon station and arriving at Gare de Strasbourg station via Strasbourg - L'Étoile Park Bus Station station. The journey, including transfers, takes approximately 7h 23m.
Lyon to Gare de Strasbourg bus services, operated by FlixBus, depart from Lyon - Gerland Bus Station.
Lyon to Gare de Strasbourg bus services, operated by FlixBus, arrive at Strasbourg - L'Étoile Park Bus Station.
Book your Lyon to Gare de Strasbourg bus tickets online with FlixBus, CTS - Compagnie des Transports Strasbourgeois and BlaBlaCar Bus.
The distance between Lyon and Gare de Strasbourg is 383.5 km. The road distance is 557 km.
BlaBlaCar Bus operates a bus from Lyon - Gerland Bus Station to Strasbourg - L'Étoile Park Bus Station every 4 hours. Tickets cost €35–60 and the journey takes 6h 50m. FlixBus also services this route 3 times a day.