Lyon to Milano Centrale Station Buses

Lyon to Milano Centrale Station buses

Travel from

Search accommodation with Expedia

Trip Overview

The average bus between Lyon and Milano Centrale Station takes 7h 35m and the fastest bus takes 6h 54m. There is a bus service every few hours from Lyon to Milano Centrale Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

7h 35m
Duration: 448 km
Distance: €44
Average price: Hourly
Frequency

Bus

best

Take the bus from Lyon - Gerland Bus Station to Milano, Autostazione Lampugnanobus BlaBlaCar Bus

6h 58m

€25–62

Lyon to Milano Centrale Station bus times

Buses run hourly between Lyon and Milano Centrale Station. The earliest departure is at 12:05 AM at night, and the last departure from Lyon is at 11:59 PM which arrives into Milano Centrale Station at 6:53 AM. All services require a transfer at Milano, Autostazione Lampugnano and take an average of 7h 35m. The schedules shown below are for the next available departures.

Departing Monday, November 9, 2026

11:59 PM → 6:53 AM
Arrives next day
6h 54m • 2 changes

Departing Tuesday, November 10, 2026

12:05 AM → 7:21 AM
7h 16m • 2 changes
1:45 AM → 8:43 AM
6h 58m • 2 changes
3:15 AM → 10:20 AM
7h 5m • 2 changes
5:40 AM → 1:01 PM
7h 21m • 2 changes
Show more

Departing Wednesday, November 11, 2026

12:05 AM → 7:21 AM
7h 16m • 2 changes
1:45 AM → 8:43 AM
6h 58m • 2 changes
3:15 AM → 10:20 AM
7h 5m • 2 changes
5:40 AM → 1:01 PM
7h 21m • 2 changes
Show more

Departing Thursday, November 12, 2026

12:05 AM → 7:21 AM
7h 16m • 2 changes
1:45 AM → 8:43 AM
6h 58m • 2 changes
3:15 AM → 10:20 AM
7h 5m • 2 changes
5:40 AM → 1:01 PM
7h 21m • 2 changes
Show more

Departing Friday, November 13, 2026

12:05 AM → 7:21 AM
7h 16m • 2 changes
1:45 AM → 8:43 AM
6h 58m • 2 changes
3:15 AM → 10:20 AM
7h 5m • 2 changes
5:40 AM → 1:01 PM
7h 21m • 2 changes
Show more

Departing Saturday, November 14, 2026

12:05 AM → 7:15 AM
7h 10m • 2 changes
1:45 AM → 8:39 AM
6h 54m • 2 changes
3:15 AM → 10:21 AM
7h 6m • 2 changes
5:40 AM → 1:09 PM
7h 29m • 2 changes
Show more

Departing Sunday, November 15, 2026

12:05 AM → 7:25 AM
7h 20m • 2 changes
1:45 AM → 8:56 AM
7h 11m • 2 changes
3:15 AM → 10:37 AM
7h 22m • 2 changes
5:40 AM → 1:02 PM
7h 22m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Lyon to Milano Centrale Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.