The average bus between Lyon and Milano Centrale Station takes 7h 41m and the fastest bus takes 6h 55m. The bus service runs several times per day from Lyon to Milano Centrale Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Lyon and Milano Centrale Station. The earliest departure is at 12:05 AM at night, and the last departure from Lyon is at 11:59 PM which arrives into Milano Centrale Station at 6:54 AM. All services require a transfer at Milano, Autostazione Lampugnano and take an average of 7h 41m. The schedules shown below are for the next available departures.


7h 32m • 2 changes
Arrives next day


7h 15m • 2 changes
Arrives next day


7h 9m • 2 changes
Arrives next day


6h 55m • 2 changes


7h 36m • 2 changes


7h 26m • 2 changes


7h 22m • 2 changes


7h 36m • 2 changes
Want to know about travelling from Lyon to Milano Centrale Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Milano Centrale Station. However, there are services departing from Lyon station and arriving at Milano Centrale Station station via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 7h 41m.
Lyon to Milano Centrale Station bus services, operated by BlaBlaCar Bus, depart from Lyon - Gerland Bus Station.
Lyon to Milano Centrale Station bus services, operated by BlaBlaCar Bus, arrive at Milano, Autostazione Lampugnano station.
The distance between Lyon and Milano Centrale Station is 340 km. The road distance is 451 km.
BlaBlaCar Bus operates a bus from Lyon - Gerland Bus Station to Milano, Autostazione Lampugnano hourly. Tickets cost €35–70 and the journey takes 6h 15m. Two other operators also service this route.