The average bus between Lyon and Pernes-les-Fontaines takes 6h 8m and the fastest bus takes 4h 49m. The bus service runs several times per day from Lyon to Pernes-les-Fontaines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Lyon and Pernes-les-Fontaines. The earliest departure is at 1:40 AM at night, and the last departure from Lyon is at 1:55 PM which arrives into Pernes-les-Fontaines at 7:30 PM. All services require a transfer at Avignon and take an average of 6h 8m. The schedules shown below are for the next available departures.



4h 49m • 3 changes



5h 24m • 3 changes



5h 29m • 3 changes



4h 55m • 3 changes



6h 29m • 3 changes



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6h 50m • 3 changes
Arrives next day



19h 15m • 3 changes



4h 55m • 3 changes



6h 50m • 3 changes
Arrives next day



16h 15m • 3 changes



6h 29m • 3 changes



4h 49m • 3 changes



5h 24m • 3 changes



5h 29m • 3 changes



6h 29m • 3 changes



4h 49m • 3 changes



5h 24m • 3 changes



5h 29m • 3 changes



6h 29m • 3 changes



4h 49m • 3 changes



5h 24m • 3 changes



5h 29m • 3 changes
Want to know about travelling from Lyon to Pernes-les-Fontaines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Pernes-les-Fontaines. However, there are services departing from Lyon station and arriving at Pernes-les-Fontaines station via Avignon. The journey, including transfers, takes approximately 6h 8m.
Lyon to Pernes-les-Fontaines bus services, operated by BlaBlaCar Bus, depart from Lyon station.
Lyon to Pernes-les-Fontaines bus services, operated by BlaBlaCar Bus, arrive at Avignon station.
The distance between Lyon and Pernes-les-Fontaines is 195.3 km. The road distance is 249 km.
FlixBus operates a bus from Lyon to Avignon every 4 hours. Tickets cost €19–35 and the journey takes 2h 40m. BlaBlaCar Bus also services this route every 4 hours.