The average bus between Lyon and Vaison-la-Romaine takes 6h 7m and the fastest bus takes 4h 43m. The bus service runs several times per day from Lyon to Vaison-la-Romaine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Lyon and Vaison-la-Romaine. The earliest departure is at 5:20 AM in the morning, and the last departure from Lyon is at 1:55 PM which arrives into Vaison-la-Romaine at 7:35 PM. All services require a transfer at Le Lac and take an average of 6h 7m. The schedules shown below are for the next available departures.


5h 25m • 2 changes


4h 43m • 2 changes


5h 45m • 2 changes


7h 25m • 2 changes


5h 25m • 2 changes


4h 43m • 2 changes


5h 45m • 2 changes


7h 25m • 2 changes


5h 25m • 2 changes


4h 43m • 2 changes


5h 45m • 2 changes


7h 25m • 2 changes


5h 25m • 2 changes


4h 43m • 2 changes


5h 45m • 2 changes


7h 25m • 2 changes
Want to know about travelling from Lyon to Vaison-la-Romaine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Vaison-la-Romaine. However, there are services departing from Lyon station and arriving at Vaison-la-Romaine station via Avignon. The journey, including transfers, takes approximately 6h 7m.
Lyon to Vaison-la-Romaine bus services, operated by FlixBus, depart from Lyon station.
Lyon to Vaison-la-Romaine bus services, operated by FlixBus, arrive at Avenue des Choralies station.
The distance between Lyon and Vaison-la-Romaine is 168.6 km. The road distance is 294 km.
You can take a bus from Lyon to Avenue des Choralies via Le Lac and PEM Gare Routière in around 5h 59m.