The average bus between Lyon and Vaison-la-Romaine takes 5h 51m and the fastest bus takes 4h 39m. The bus service runs several times per day from Lyon to Vaison-la-Romaine. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Lyon and Vaison-la-Romaine. The earliest departure is at 4:20 AM at night, and the last departure from Lyon is at 1:50 PM which arrives into Vaison-la-Romaine at 7:35 AM. All services require a transfer at Le Lac and take an average of 5h 51m. The schedules shown below are for the next available departures.


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5h 14m • 2 changesWant to know about travelling from Lyon to Vaison-la-Romaine? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Vaison-la-Romaine. However, there are services departing from Lyon station and arriving at Cave la Romaine station via Avignon station. The journey, including transfers, takes approximately 5h 51m.
Lyon to Vaison-la-Romaine bus services, operated by FlixBus, depart from Lyon station.
Lyon to Vaison-la-Romaine bus services, operated by ZOU! Proximité, arrive at Cave la Romaine station.
The distance between Lyon and Vaison-la-Romaine is 168.6 km. The road distance is 201 km.
You can take a bus from Lyon to Cave la Romaine via Le Lac and PEM Gare Routière in around 5h 54m.