The average bus between Lyon and Vatican City takes 15h 37m and the fastest bus takes 14h 55m. The bus service runs several times per day from Lyon to Vatican City. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 4 times a day between Lyon and Vatican City. The earliest departure is at 1:15 AM at night, and the last departure from Lyon is at 3:30 PM which arrives into Vatican City at 7:40 AM. All services require a transfer, and take on average 15h 37m. The schedules shown below are for the next available departures.

15h 38m • 1 change

15h 23m • 1 change
Arrives next day

14h 57m • 1 change
Arrives next day

16h 18m • 1 change

15h 38m • 1 change

15h 23m • 1 change
Arrives next day

15h 17m • 1 change
Arrives next day

16h 18m • 1 change

15h 38m • 1 change

15h 23m • 1 change
Arrives next day

15h 17m • 1 change
Arrives next day

16h 18m • 1 change

15h 38m • 1 change

15h 23m • 1 change
Arrives next day

14h 57m • 1 change
Arrives next day

16h 10m • 1 change
Want to know about travelling from Lyon to Vatican City? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Vatican City. However, there are services departing from Lyon station and arriving at Vatican City station via Roma, Autostazione Tiburtina. The journey, including transfers, takes approximately 15h 37m.
Lyon to Vatican City bus services, operated by Itabus S.p.A., depart from Gare de Lyon-Perrache station.
Lyon to Vatican City bus services, operated by Itabus S.p.A., arrive at Roma, Autostazione Tiburtina station.
Book your Lyon to Vatican City bus tickets online with Itabus S.p.A., ATAC S.p.A. Azienda per la mobilità and 2 other operators.
The distance between Lyon and Vatican City is 744.5 km. The road distance is 1,039 km.
Itabus S.p.A. operates a bus from Gare de Lyon-Perrache to Roma, Autostazione Tiburtina twice daily. Tickets cost €60–120 and the journey takes 14h 30m. Two other operators also service this route.