The average bus between Lyon and Vendôme takes 12h 38m and the fastest bus takes 9h 45m. The bus service runs several times per day from Lyon to Vendôme. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Lyon and Vendôme. The earliest departure is at 3:05 AM at night, and the last departure from Lyon is at 8:45 PM which arrives into Vendôme at 7:33 AM. All services require a transfer at Tours and take an average of 12h 38m. The schedules shown below are for the next available departures.


14h 32m • 2 changes


9h 45m • 2 changes
Arrives next day


10h 48m • 2 changes


12h 32m • 2 changes


9h 45m • 2 changes
Arrives next day


12h 18m • 2 changes
Want to know about travelling from Lyon to Vendôme? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Lyon to Vendôme. However, there are services departing from Lyon station and arriving at Vendôme station via Tours. The journey, including transfers, takes approximately 12h 38m.
Lyon to Vendôme bus services, operated by FlixBus, depart from Lyon station.
Lyon to Vendôme bus services, operated by FlixBus, arrive at Vendome station.
The distance between Lyon and Vendôme is 366.8 km. The road distance is 577 km.
You can take a bus from Lyon to Vendome via Tours, Vaucanson, Gare de Tours 4, and Tours in around 8h 38m.