The average bus between Maastricht and Karlsruhe takes 7h 2m and the fastest bus takes 5h 50m. The bus service runs several times per day from Maastricht to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Maastricht and Karlsruhe. The earliest departure is at 1:15 AM at night, and the last departure from Maastricht is at 8:00 PM which arrives into Karlsruhe at 3:00 AM. All services require a transfer, and take on average 7h 2m. The schedules shown below are for the next available departures.

5h 35m • 1 change

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7h 15m • 1 change

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7h 15m • 1 change

6h 10m • 1 change

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5h 50m • 1 change

7h 15m • 1 change

6h 10m • 1 change

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7h 15m • 1 change
Want to know about travelling from Maastricht to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Maastricht to Karlsruhe. However, there are services departing from Maastricht station and arriving at Karlsruhe station via Frankfurt central train station station. The journey, including transfers, takes approximately 7h 2m.
Maastricht to Karlsruhe bus services, operated by FlixBus, depart from Maastricht station.
Maastricht to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Book your Maastricht to Karlsruhe bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Maastricht and Karlsruhe is 282.1 km. The road distance is 441 km.
You can take a bus from Maastricht to Karlsruhe central train station via Frankfurt central train station in around 6h 47m.