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Mackinaw City to Buffalo buses

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Trip Overview

The bus between Mackinaw City and Buffalo takes 24h 45m. The bus runs, on average, 6 times per week from Mackinaw City to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

24h 45m
Duration
719 mi
Distance
6 times a week
Frequency

Mackinaw City to Buffalo bus times

Buses run 6 times a week between Mackinaw City and Buffalo. The service departs Mackinaw City at 7:15 AM in the morning, which arrives into Buffalo at 08:00:00. All services require a transfer at East Lansing and take an average of 24h 45m. The schedules shown below are for the next available departures.

Departing Sunday, November 8, 2026

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    Arrives next day

    Indian TrailsAmtrakGreyhound USAGreyhound USA24h 45m • 3 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Indian TrailsAmtrakGreyhound USAGreyhound USA24h 45m • 3 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Indian TrailsAmtrakGreyhound USAGreyhound USA24h 45m • 3 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Indian TrailsAmtrakGreyhound USAGreyhound USA24h 45m • 3 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Indian TrailsAmtrakGreyhound USAGreyhound USA24h 45m • 3 changes

Frequently asked questions

Want to know about travelling from Mackinaw City to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mackinaw City to Buffalo.ExpandLaunch map view
  • Distance: 719.4 mi
  • Duration: 24h 45m

What companies run services between Mackinaw City, MI, USA and Buffalo, NY, USA?

You can take a bus from Mackinaw City to Buffalo via East Lansing, East Lansing Amtrak Station, Toledo Bus Stop, and Cleveland Bus Station in around 17h 50m.

Operators