Madison to Louisville Buses

Madison to Louisville buses

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Trip Overview

The average bus between Madison and Louisville takes 11h 6m and the fastest bus takes 10h 30m. The bus service runs several times per day from Madison to Louisville. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 6m
Duration: 456 mi
Distance: $108
Average price: 5 times a day
Frequency

Bus

best

Take the bus from 250 N. Lake St - Madison UW Campus to W Jackson Blvd, after S Clinton Stbus Van Galder
Take the bus from Chicago Bus Station to Louisville Bus Stationbus Greyhound US0100

11h 12m

$66–131

Madison to Louisville bus times

Buses run 5 times a day between Madison and Louisville. The earliest departure is at 1:30 AM at night, and the last departure from Madison is at 6:30 PM which arrives into Louisville at 6:45 AM. All services require a transfer at W Jackson Blvd, after S Clinton St and take an average of 11h 6m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

6:30 PM → 6:45 AM
Arrives next day
11h 15m • 1 change

Departing Saturday, October 10, 2026

1:30 AM → 1:15 PM
10h 45m • 1 change
5:30 AM → 6:00 PM
11h 30m • 1 change
10:30 AM → 10:00 PM
10h 30m • 1 change
12:30 PM → 1:15 AM
Arrives next day
11h 45m • 1 change
Show more

Departing Sunday, October 11, 2026

1:30 AM → 1:15 PM
10h 45m • 1 change
5:30 AM → 6:00 PM
11h 30m • 1 change
10:30 AM → 10:00 PM
10h 30m • 1 change
12:30 PM → 1:15 AM
Arrives next day
11h 45m • 1 change
Show more

Departing Monday, October 12, 2026

1:30 AM → 1:15 PM
10h 45m • 1 change
5:30 AM → 6:00 PM
11h 30m • 1 change
10:30 AM → 10:00 PM
10h 30m • 1 change
12:30 PM → 1:15 AM
Arrives next day
11h 45m • 1 change
Show more

Departing Tuesday, October 13, 2026

1:30 AM → 1:15 PM
10h 45m • 1 change
5:30 AM → 6:00 PM
11h 30m • 1 change
10:30 AM → 10:00 PM
10h 30m • 1 change
6:30 PM → 6:45 AM
Arrives next day
11h 15m • 1 change

Departing Wednesday, October 14, 2026

1:30 AM → 1:15 PM
10h 45m • 1 change
5:30 AM → 6:00 PM
11h 30m • 1 change
10:30 AM → 10:00 PM
10h 30m • 1 change
6:30 PM → 6:45 AM
Arrives next day
11h 15m • 1 change

Departing Thursday, October 15, 2026

1:30 AM → 1:15 PM
10h 45m • 1 change
5:30 AM → 6:00 PM
11h 30m • 1 change
10:30 AM → 10:00 PM
10h 30m • 1 change
12:30 PM → 1:15 AM
Arrives next day
11h 45m • 1 change

Frequently asked questions

Want to know about travelling from Madison to Louisville? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Madison to Louisville buses

Trip Overview

Bus