The average bus between Madrid Airport (MAD) and Santa Ana takes 2h 55m and the fastest bus takes 2h 23m. There is a bus service every few hours from Madrid Airport (MAD) to Santa Ana. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Madrid Airport (MAD) and Santa Ana. The earliest departure is at 7:00 AM in the morning, and the last departure from Madrid Airport (MAD) is at 11:50 PM which arrives into Santa Ana at 7:54 AM. All services require a transfer at Estación De Atocha and take an average of 2h 55m. The schedules shown below are for the next available departures.
Arrives next day


2h 35m • 2 changes
Arrives next day


8h 4m • 2 changes


2h 23m • 2 changes


2h 35m • 2 changes


2h 35m • 2 changes


2h 35m • 2 changes


2h 23m • 2 changes


2h 35m • 2 changes


2h 35m • 2 changes


2h 35m • 2 changes


2h 41m • 2 changes


2h 35m • 2 changes


2h 50m • 2 changes


2h 50m • 2 changes


2h 23m • 2 changes


2h 35m • 2 changes


2h 35m • 2 changes


2h 35m • 2 changes
Want to know about travelling from Madrid Airport (MAD) to Santa Ana? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid Airport (MAD) to Santa Ana. However, there are services departing from Madrid Airport (MAD) station and arriving at Santa Ana station via Estación De Atocha. The journey, including transfers, takes approximately 2h 55m.
Madrid Airport (MAD) to Santa Ana bus services, operated by Empresa Municipal de Transportes, depart from Aeropuerto T4 station.
Madrid Airport (MAD) to Santa Ana bus services, operated by Empresa Municipal de Transportes, arrive at Ctra.M238-Las Arcas Del Pilar station.
The distance between Madrid Airport (MAD) and Santa Ana is 52.5 km. The road distance is 104 km.
You can take a bus from Aeropuerto T4 to Ctra.M238-Las Arcas Del Pilar via Estación De Atocha, Estación Sur, and Estación Sur De Autobuses in around 3h 2m.