The average bus between Madrid Airport (MAD) and Santander takes 6h 33m and the fastest bus takes 6h 10m. The bus service runs several times per day from Madrid Airport (MAD) to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Madrid Airport (MAD) and Santander. The earliest departure is at 5:58 AM in the morning, and the last departure from Madrid Airport (MAD) is at 11:42 PM which arrives into Santander at 6:30 AM. All services require a transfer, and take on average 6h 33m. The schedules shown below are for the next available departures.

6h 39m • 1 change

6h 12m • 1 change

6h 16m • 1 change

6h 37m • 1 change

6h 39m • 1 change

6h 12m • 1 change

6h 16m • 1 change

6h 37m • 1 change

6h 39m • 1 change

6h 12m • 1 change

6h 16m • 1 change

6h 37m • 1 change

6h 39m • 1 change

6h 12m • 1 change

6h 16m • 1 change

6h 37m • 1 change

6h 30m • 1 change

6h 10m • 1 change

6h 18m • 1 change

6h 27m • 1 change
Want to know about travelling from Madrid Airport (MAD) to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid Airport (MAD) to Santander. However, there are services departing from Madrid Airport (MAD) station and arriving at Santander station via Estación de autobuses de Santander. The journey, including transfers, takes approximately 6h 33m.
Madrid Airport (MAD) to Santander bus services, operated by Empresa Municipal de Transportes, depart from Madrid, Avenida de América station.
Madrid Airport (MAD) to Santander bus services, operated by Empresa Municipal de Transportes, arrive at Estación de autobuses de Santander station.
The distance between Madrid Airport (MAD) and Santander is 331.1 km. The road distance is 433 km.
ALSA operates a bus from Madrid, Avenida de América to Estación de autobuses de Santander every 4 hours. Tickets cost €30–50 and the journey takes 5h 30m.