The average bus between Madrid Atocha Station and Santander takes 6h 26m and the fastest bus takes 5h 57m. The bus service runs several times per day from Madrid Atocha Station to Santander. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Madrid Atocha Station and Santander. The earliest departure is at 12:04 AM at night, and the last departure from Madrid Atocha Station is at 6:00 PM which arrives into Santander at 12:00 AM. All services require a transfer at Basílica De Atocha and take an average of 6h 26m. The schedules shown below are for the next available departures.

6h 17m • 1 change

6h • 1 change

6h 2m • 1 change

6h 17m • 1 change

6h 25m • 1 change

6h 17m • 1 change

6h • 1 change

6h 2m • 1 change

6h 25m • 1 change

6h 17m • 1 change

6h • 1 change

6h 2m • 1 change

6h 25m • 1 change

6h 17m • 1 change

6h • 1 change

6h 2m • 1 change

6h 25m • 1 change

6h 17m • 1 change

6h • 1 change

6h 2m • 1 change

6h 20m • 1 change

5h 57m • 1 change

5h 57m • 1 change

6h 18m • 1 change
Want to know about travelling from Madrid Atocha Station to Santander? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid Atocha Station to Santander. However, there are services departing from Madrid Atocha Station station and arriving at Santander station via Estación de autobuses de Santander. The journey, including transfers, takes approximately 6h 26m.
Madrid Atocha Station to Santander bus services, operated by Empresa Municipal de Transportes, depart from Madrid, Avenida de América station.
Madrid Atocha Station to Santander bus services, operated by Empresa Municipal de Transportes, arrive at Estación de autobuses de Santander station.
The distance between Madrid Atocha Station and Santander is 340.5 km. The road distance is 413 km.
ALSA operates a bus from Madrid, Avenida de América to Estación de autobuses de Santander every 4 hours. Tickets cost €30–50 and the journey takes 5h 30m.