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Madrid to Florence buses

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Trip Overview

The average bus between Madrid and Florence takes 38h 28m and the fastest bus takes 37h 51m. The bus runs, on average, 5 times per week from Madrid to Florence. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

38h 28m
Duration
1,733 km
Distance
€185
Average price
5 times a week
Frequency

Madrid to Florence bus times

Buses run 5 times a week between Madrid and Florence. The earliest departure is at 5:42 AM in the morning, and the last departure from Madrid is at 5:48 AM which arrives into Florence at 7:40 PM. All services require a transfer at Estación Sur and take an average of 38h 28m. The schedules shown below are for the next available departures.

Departing Saturday, November 7, 2026

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    Arrives next day

    Empresa Municipal de TransportesFlixBusFlixBus37h 51m • 2 changes

Departing Monday, November 9, 2026

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    Arrives next day

    Empresa Municipal de TransportesFlixBusFlixBus37h 57m • 2 changes

Departing Tuesday, November 10, 2026

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    Arrives next day

    Empresa Municipal de TransportesFlixBusFlixBus39h 17m • 2 changes

Departing Wednesday, November 11, 2026

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    Arrives next day

    Empresa Municipal de TransportesFlixBusFlixBus39h 17m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives next day

    Empresa Municipal de TransportesFlixBusFlixBus37h 57m • 2 changes

Frequently asked questions

Want to know about travelling from Madrid to Florence? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Florence.ExpandLaunch map view
  • Distance: 1,732.6 km
  • Duration: 38h 28m

What companies run services between Madrid, Spain and Florence, Italy?

You can take a bus from Neptuno to Florence Villa Constanza Bus Station via Estación Sur, Madrid, and Genoa in around 25h 39m.

Operators