Rome2Rio

Madrid to Istanbul buses

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Trip Overview

The bus between Madrid and Istanbul takes 3d 10h. The bus runs, on average, once a week from Madrid to Istanbul. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3d 10h
Duration
4,072 km
Distance
₺18,165
Average price
Once a week
Frequency

Madrid to Istanbul bus times

Buses run once a week between Madrid and Istanbul. The service departs Madrid at 5:42 AM in the morning, which arrives into Istanbul at 18:00:00. All services require a transfer at Estación Sur and take an average of 3d 10h. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +3 days

    Empresa Municipal de TransportesBlaBlaCar BusFlixBusAlpar Turizm3d 10h • 3 changes

Frequently asked questions

Want to know about travelling from Madrid to Istanbul? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Istanbul.ExpandLaunch map view
  • Distance: 4,072 km
  • Duration: 3d 10h

What companies run services between Madrid, Spain and Istanbul, Turkey?

You can take a bus from Neptuno to Istanbul via Estación Sur, Estación Sur de Autobuses, Karlsruhe central train station, and Munich in around 2d 11h.

Operators