Rome2Rio

Madrid to Prague buses

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Trip Overview

The average bus between Madrid and Prague takes 2d 1h and the fastest bus takes 2d. The bus runs, on average, 2 times per week from Madrid to Prague. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 1h
Duration
2,443 km
Distance
Kč 4,928
Average price
Twice a week
Frequency

Madrid to Prague bus times

Buses run twice a week between Madrid and Prague. The earliest departure is at 5:42 AM in the morning, and the last departure from Madrid is at 5:48 AM which arrives into Prague at 6:20 AM. All services require a transfer at Estación Sur and take an average of 2d 1h. The schedules shown below are for the next available departures.

Departing Saturday, October 24, 2026

  •  → 

    Arrives +2 days

    Empresa Municipal de TransportesBlaBlaCar BusRegioJet2d 1h • 2 changes

Departing Tuesday, October 27, 2026

  •  → 

    Arrives +2 days

    Empresa Municipal de TransportesBlaBlaCar BusRegioJet2d • 2 changes

Frequently asked questions

Want to know about travelling from Madrid to Prague? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Prague.ExpandLaunch map view
  • Distance: 2,443.3 km
  • Duration: 2d 1h

What companies run services between Madrid, Spain and Prague, Czechia?

You can take a bus from Neptuno to Prague Wilsonova Bus Station via Estación Sur, Estación Sur de Autobuses, and Strasbourg Central Bus Station Place de l’Etoile in around 34h 5m.

Operators