The average bus between Madrid (Station) and Lyon takes 17h 29m and the fastest bus takes 17h. The bus service runs several times per day from Madrid (Station) to Lyon. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Madrid (Station) and Lyon. The earliest departure is at 8:31 AM in the morning, and the last departure from Madrid (Station) is at 11:21 PM which arrives into Lyon at 3:30 PM. All services require a transfer at Avenida De América and take an average of 17h 29m. The schedules shown below are for the next available departures.
Arrives next day

17h 1m • 1 change
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16h 9m • 1 change
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17h 24m • 1 change
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17h 1m • 1 change
Arrives next day

16h 9m • 1 change
Arrives next day

17h 24m • 1 change
Arrives next day

17h 1m • 1 change
Arrives next day

16h 9m • 1 change
Arrives next day

17h 24m • 1 change
Arrives next day

17h 1m • 1 change
Arrives next day

16h 9m • 1 change
Arrives next day

17h 24m • 1 change
Arrives next day

17h 1m • 1 change
Arrives next day

16h 9m • 1 change
Want to know about travelling from Madrid (Station) to Lyon? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid (Station) to Lyon. However, there are services departing from Madrid (Station) station and arriving at Lyon station via Lyon - Gerland Bus Station station. The journey, including transfers, takes approximately 17h 29m.
Madrid (Station) to Lyon bus services, operated by Empresa Municipal de Transportes, depart from Madrid - Barajas Airport T4 station.
Madrid (Station) to Lyon bus services, operated by Empresa Municipal de Transportes, arrive at Lyon - Gerland Bus Station.
The distance between Madrid (Station) and Lyon is 908.3 km. The road distance is 1,257 km.
BlaBlaCar Bus operates a bus from Madrid - Barajas Airport T4 to Lyon - Gerland Bus Station 4 times a day. Tickets cost €110–200 and the journey takes 16h 45m. FlixBus also services this route once daily.