The average bus between Madrid (Station) and Santiago de Compostela Cathedral takes 9h 58m and the fastest bus takes 8h 22m. The bus service runs several times per day from Madrid (Station) to Santiago de Compostela Cathedral. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Madrid (Station) and Santiago de Compostela Cathedral. The earliest departure is at 12:01 AM at night, and the last departure from Madrid (Station) is at 5:27 PM which arrives into Santiago de Compostela Cathedral at 2:30 AM. All services require a transfer at Hospital De La Princesa and take an average of 9h 58m. The schedules shown below are for the next available departures.
Arrives next day

8h 22m • 1 change
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9h 2m • 1 change
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8h 22m • 1 change
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9h 2m • 1 change
Arrives next day

8h 22m • 1 change
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9h 2m • 1 change
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8h 22m • 1 change
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9h 2m • 1 change
Want to know about travelling from Madrid (Station) to Santiago de Compostela Cathedral? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid (Station) to Santiago de Compostela Cathedral. However, there are services departing from Madrid (Station) station and arriving at Santiago de Compostela Cathedral station via Estación de autobuses de Santiago de Compostela. The journey, including transfers, takes approximately 9h 58m.
Madrid (Station) to Santiago de Compostela Cathedral bus services, operated by Empresa Municipal de Transportes, depart from Madrid Moncloa station.
Madrid (Station) to Santiago de Compostela Cathedral bus services, operated by Empresa Municipal de Transportes, arrive at Estación de autobuses de Santiago de Compostela station.
The distance between Madrid (Station) and Santiago de Compostela Cathedral is 487.3 km. The road distance is 672 km.
ALSA operates a bus from Madrid Moncloa to Estación de autobuses de Santiago de Compostela twice daily. Tickets cost €55–90 and the journey takes 7h 50m.