The average bus between Madrid and Brindisi takes 39h 40m and the fastest bus takes 39h 30m. The bus runs, on average, 6 times per week from Madrid to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Madrid and Brindisi. The earliest departure is at 5:05 PM in the evening, and the last departure from Madrid is at 6:05 PM which arrives into Brindisi at 9:35 AM. All services require a transfer, and take on average 39h 40m. The schedules shown below are for the next available departures.
Want to know about travelling from Madrid to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid to Brindisi. However, there are services departing from Madrid station and arriving at Brindisi Istituto Professionale Falcone station via Milan station. The journey, including transfers, takes approximately 39h 40m.
Madrid to Brindisi bus services, operated by FlixBus, depart from Madrid station.
Madrid to Brindisi bus services, operated by Itabus S.p.A., arrive at Brindisi Istituto Professionale Falcone station.
Book your Madrid to Brindisi bus tickets online with Omio and FlixBus.
The distance between Madrid and Brindisi is 1824.5 km. The road distance is 2426 km.
You can take a bus from Madrid to Brindisi Istituto Professionale Falcone via Milan Lampugnano in around 38h 40m.