The average bus between Madrid and Brindisi takes 42h 28m and the fastest bus takes 40h 45m. The bus runs, on average, 6 times per week from Madrid to Brindisi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 6 times a week between Madrid and Brindisi. The earliest departure is at 5:05 PM in the evening, and the last departure from Madrid is at 5:05 PM which arrives into Brindisi at 11:50 AM. All services require a transfer, and take on average 42h 28m. The schedules shown below are for the next available departures.
Want to know about travelling from Madrid to Brindisi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid to Brindisi. However, there are services departing from Madrid station and arriving at Brindisi station via Milan. The journey, including transfers, takes approximately 42h 28m.
Madrid to Brindisi bus services, operated by FlixBus, depart from Madrid station.
Madrid to Brindisi bus services, operated by FlixBus, arrive at Brindisi station.
Book your Madrid to Brindisi bus tickets online with FlixBus.
The distance between Madrid and Brindisi is 1,824.5 km. The road distance is 2,662 km.
You can take a bus from Madrid to Brindisi via Milano, Autostazione Lampugnano in around 37h 30m.
