The average bus between Madrid and Guarnizo takes 7h 7m and the fastest bus takes 6h 5m. The bus service runs several times per day from Madrid to Guarnizo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run every 4 hours between Madrid and Guarnizo. The earliest departure is at 12:30 AM at night, and the last departure from Madrid is at 6:30 PM which arrives into Guarnizo at 12:35 AM. All services require a transfer, and take on average 7h 7m. The schedules shown below are for the next available departures.

6h 35m • 1 change

6h 26m • 1 change

6h 11m • 1 change

6h 11m • 1 change

6h 35m • 1 change

6h 26m • 1 change

6h 11m • 1 change

6h 11m • 1 change

6h 35m • 1 change

6h 26m • 1 change

6h 11m • 1 change

6h 11m • 1 change

6h 35m • 1 change

6h 26m • 1 change

6h 11m • 1 change

6h 11m • 1 change

6h 35m • 1 change

6h 26m • 1 change

6h 11m • 1 change

6h 11m • 1 change

6h 50m • 1 change

6h 41m • 1 change

6h 5m • 1 change

6h 11m • 1 change

6h 50m • 1 change

6h 41m • 1 change

6h 5m • 1 change

6h 11m • 1 change
Want to know about travelling from Madrid to Guarnizo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid to Guarnizo. However, there are services departing from Madrid station and arriving at Guarnizo station via Estación de autobuses de Santander. The journey, including transfers, takes approximately 7h 7m.
Madrid to Guarnizo bus services, operated by ALSA, depart from Madrid, Avenida de América station.
Madrid to Guarnizo bus services, operated by ALSA, arrive at Estación de autobuses de Santander station.
The distance between Madrid and Guarnizo is 331.9 km. The road distance is 419 km.
ALSA operates a bus from Madrid, Avenida de América to Estación de autobuses de Santander every 4 hours. Tickets cost €30–70 and the journey takes 5h 30m.