The average bus between Madrid and Lille takes 20h 40m and the fastest bus takes 20h 10m. The bus service runs several times per day from Madrid to Lille. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Madrid and Lille. The earliest departure is at 12:50 PM in the afternoon, and the last departure from Madrid is at 6:25 PM which arrives into Lille at 5:20 PM. All services require a transfer at Paris and take an average of 20h 40m. The schedules shown below are for the next available departures.
Arrives next day

22h 55m • 1 change
Arrives next day

22h 10m • 1 change
Arrives next day

22h 55m • 1 change
Arrives next day

22h 55m • 1 change
Arrives next day

22h 10m • 1 change
Arrives next day

22h 55m • 1 change
Arrives next day

22h 55m • 1 change
Arrives next day

22h 10m • 1 change
Arrives next day

22h 55m • 1 change
Want to know about travelling from Madrid to Lille? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid to Lille. However, there are services departing from Madrid station and arriving at Lille station via Paris. The journey, including transfers, takes approximately 20h 40m.
Madrid to Lille bus services, operated by FlixBus, depart from Madrid station.
Madrid to Lille bus services, operated by FlixBus, arrive at Lille - Europe Train Station.
Book your Madrid to Lille bus tickets online with FlixBus and BlaBlaCar Bus.
The distance between Madrid and Lille is 1,250.9 km. The road distance is 1,468 km.
You can take a bus from Madrid to Lille - Europe Train Station via Paris and Paris - Bercy-Seine Bus Station in around 19h 27m.