The average bus between Madrid and Lisbon Region takes 8h 7m and the fastest bus takes 7h 34m. The bus service runs several times per day from Madrid to Lisbon Region. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Madrid and Lisbon Region. The earliest departure is at 12:55 AM at night, and the last departure from Madrid is at 11:45 PM which arrives into Lisbon Region at 6:53 AM. All services require a transfer at Lisbon - Oriente and take an average of 8h 7m. The schedules shown below are for the next available departures.

7h 14m • 1 change
Arrives next day

7h 19m • 1 change
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7h 8m • 1 change

7h 11m • 1 change

6h 52m • 1 change

7h 14m • 1 change
Arrives next day

7h 19m • 1 change

7h 11m • 1 change

6h 52m • 1 change

7h 14m • 1 change
Arrives next day

7h 19m • 1 change

7h 11m • 1 change

6h 52m • 1 change

7h 14m • 1 change
Arrives next day

7h 19m • 1 change

7h 3m • 1 change

6h 34m • 1 change

7h 12m • 1 change
Arrives next day

7h 17m • 1 change

7h 3m • 1 change

6h 34m • 1 change

7h 12m • 1 change
Arrives next day

7h 17m • 1 change
Want to know about travelling from Madrid to Lisbon Region? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid to Lisbon Region. However, there are services departing from Madrid station and arriving at Lisbon Region station via Lisbon - Oriente. The journey, including transfers, takes approximately 8h 7m.
Madrid to Lisbon Region bus services, operated by BlaBlaCar Bus, depart from Estación Sur de Autobuses station.
Madrid to Lisbon Region bus services, operated by BlaBlaCar Bus, arrive at Lisbon - Oriente station.
The distance between Madrid and Lisbon Region is 502.9 km. The road distance is 610 km.
BlaBlaCar Bus operates a bus from Estación Sur de Autobuses to Lisbon - Oriente 4 times a day. Tickets cost €50–95 and the journey takes 7h 29m.