The average bus between Madrid and Lisbon Region takes 8h 28m and the fastest bus takes 7h 51m. The bus service runs several times per day from Madrid to Lisbon Region. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a day between Madrid and Lisbon Region. The earliest departure is at 8:05 AM in the morning, and the last departure from Madrid is at 11:55 PM which arrives into Lisbon Region at 8:18 AM. All services require a transfer at Lisbon and take an average of 8h 28m. The schedules shown below are for the next available departures.

8h 40m • 1 change
8h 58m • 1 change
8h 15m • 1 change
7h 53m • 1 change
8h 45m • 1 change
8h 59m • 1 change
8h 12m • 1 change
7h 51m • 1 change
8h 46m • 1 change
8h 54m • 1 change
8h 10m • 1 change
7h 53m • 1 change
8h 46m • 1 change
8h 54m • 1 change
7h 53m • 1 changeArrives next day

8h 25m • 1 change
8h 46m • 1 change
8h 54m • 1 change
7h 53m • 1 changeArrives next day

8h 25m • 1 changeWant to know about travelling from Madrid to Lisbon Region? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid to Lisbon Region. However, there are services departing from Madrid station and arriving at Lisbon station via Lisbon station. The journey, including transfers, takes approximately 8h 28m.
Madrid to Lisbon Region bus services, operated by FlixBus, depart from Madrid station.
Madrid to Lisbon Region bus services, operated by FlixBus, arrive at Lisbon station.
Book your Madrid to Lisbon Region bus tickets online with 12go.asia.
The distance between Madrid and Lisbon Region is 502.9 km. The road distance is 611 km.
FlixBus operates a bus from Madrid to Lisbon every 4 hours. Tickets cost €50–80 and the journey takes 7h 10m.