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Madrid to Medellín buses

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Trip Overview

The average bus between Madrid and Medellín takes 11h 40m and the fastest bus takes 8h 15m. There is at least one bus per day from Madrid to Medellín. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

11h 40m
Duration
324 km
Distance
€36
Average price
Once daily
Frequency

Madrid to Medellín bus times

Buses run once daily between Madrid and Medellín. The earliest departure is at 8:30 AM in the morning, and the last departure from Madrid is at 4:30 PM which arrives into Medellín at 7:10 AM. All services require a transfer, and take on average 11h 40m. The schedules shown below are for the next available departures.

Departing Wednesday, October 21, 2026

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    Autocares Grupo SamarInterbus8h 15m • 1 change

Departing Thursday, October 22, 2026

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    Autocares Grupo SamarInterbus8h 15m • 1 change

Departing Friday, October 23, 2026

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    Arrives next day

    Autocares Grupo SamarInterbus17h 50m • 1 change

Departing Sunday, October 25, 2026

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    Autocares Grupo SamarInterbus9h 50m • 1 change
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    Arrives next day

    Autocares Grupo SamarInterbus14h 40m • 1 change

Departing Monday, October 26, 2026

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    Arrives next day

    Autocares Grupo SamarInterbus14h 40m • 1 change

Departing Tuesday, October 27, 2026

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    Autocares Grupo SamarInterbus8h 15m • 1 change

Frequently asked questions

Want to know about travelling from Madrid to Medellín? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Medellín.ExpandLaunch map view
  • Distance: 324 km
  • Duration: 11h 40m

What companies run services between Madrid, Spain and Medellín, Spain?

Autocares Grupo Samar operates a bus from Estación Sur de Autobuses to Don Benito twice daily. Tickets cost €30–45 and the journey takes 4h 15m.

Operators