The average bus between Madrid and Palos de la Frontera takes 10h 28m and the fastest bus takes 7h 44m. The bus service runs several times per day from Madrid to Palos de la Frontera. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Madrid and Palos de la Frontera. The earliest departure is at 11:00 AM in the morning, and the last departure from Madrid is at 11:59 PM which arrives into Palos de la Frontera at 9:43 AM. All services require a transfer, and take on average 10h 28m. The schedules shown below are for the next available departures.

8h 43m • 1 change
Arrives next day

15h 59m • 1 change
Arrives next day

7h 44m • 1 change

8h 43m • 1 change
Arrives next day

15h 59m • 1 change
Arrives next day

7h 44m • 1 change

8h 43m • 1 change
Arrives next day

15h 59m • 1 change
Arrives next day

7h 44m • 1 change

8h 43m • 1 change
Arrives next day

15h 59m • 1 change
Arrives next day

7h 44m • 1 change
Want to know about travelling from Madrid to Palos de la Frontera? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid to Palos de la Frontera. However, there are services departing from Madrid station and arriving at Palos de la Frontera station via Huelva. The journey, including transfers, takes approximately 10h 28m.
Madrid to Palos de la Frontera bus services, operated by Socibus, depart from Estación Sur de Autobuses station.
Madrid to Palos de la Frontera bus services, operated by Socibus, arrive at Huelva station.
The distance between Madrid and Palos de la Frontera is 449.5 km. The road distance is 644 km.
Socibus operates a bus from Estación Sur de Autobuses to Huelva 3 times a day. Tickets cost €40–75 and the journey takes 7h 26m.