Rome2Rio

Madrid to Province of Rome (Region) buses

Find Transport to Province of Rome (Region)

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Trip Overview

The average bus between Madrid and Province of Rome (Region) takes 37h 31m and the fastest bus takes 37h 17m. The bus runs, on average, 5 times per week from Madrid to Province of Rome (Region). The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

37h 31m
Duration
2,038 km
Distance
€206
Average price
5 times a week
Frequency

Madrid to Province of Rome (Region) bus times

Buses run 5 times a week between Madrid and Province of Rome (Region). The service departs Madrid at 6:05 PM in the evening, which arrives into Province of Rome (Region) at 08:22:16. All services require a transfer at Genoa and take an average of 37h 31m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusCotral S.p.A.37h 17m • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusCotral S.p.A.38h 15m • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusCotral S.p.A.37h 32m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusCotral S.p.A.37h 17m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusCotral S.p.A.37h 17m • 2 changes

Frequently asked questions

Want to know about travelling from Madrid to Province of Rome (Region)? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Province of Rome (Region).ExpandLaunch map view
  • Distance: 2,037.8 km
  • Duration: 37h 31m

What companies run services between Madrid, Spain and Province of Rome (Region), Lazio, Italy?

You can take a bus from Madrid to FONTE NUOVA | Via Palombarese Via Liguria # f13973 via Genoa and Roma, Autostazione Tiburtina in around 29h 52m.

Operators