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The average bus between Madrid and Santa María de Cayón takes 7h 52m and the fastest bus takes 7h 35m. The bus service runs several times per day from Madrid to Santa María de Cayón. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Madrid and Santa María de Cayón. The earliest departure is at 12:30 AM at night, and the last departure from Madrid is at 3:00 PM which arrives into Santa María de Cayón at 10:37 PM. All services require a transfer, and take on average 7h 52m. The schedules shown below are for the next available departures.
Want to know about travelling from Madrid to Santa María de Cayón? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Madrid to Santa María de Cayón. However, there are services departing from Madrid, Avenida de América station and arriving at Estación de autobuses de Santander station via Estación de autobuses de Santander station. The journey, including transfers, takes approximately 7h 52m.
Madrid to Santa María de Cayón bus services, operated by ALSA, depart from Madrid, Avenida de América station.
Madrid to Santa María de Cayón bus services, operated by ALSA, arrive at Estación de autobuses de Santander station.
Book your Madrid to Santa María de Cayón bus tickets online with Omio.
The distance between Madrid and Santa María de Cayón is 322 km. The road distance is 373 km.
ALSA operates a bus from Madrid, Avenida de América to Estación de autobuses de Santander every 4 hours. Tickets cost €30–55 and the journey takes 5h 30m.
