Rome2Rio

Madrid to Syracuse buses

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Trip Overview

The bus between Madrid and Syracuse takes 2d 4h. The bus runs, on average, 5 times per week from Madrid to Syracuse. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d 4h
Duration
3,093 km
Distance
€327
Average price
5 times a week
Frequency

Madrid to Syracuse bus times

Buses run 5 times a week between Madrid and Syracuse. The service departs Madrid at 6:05 PM in the evening, which arrives into Syracuse at 23:14:00. All services require a transfer at Milano, Autostazione Lampugnano and take an average of 2d 4h. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusInterbus2d 4h • 2 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusInterbus2d 4h • 2 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusInterbus2d 4h • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusInterbus2d 4h • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    FlixBusFlixBusInterbus2d 4h • 2 changes

Frequently asked questions

Want to know about travelling from Madrid to Syracuse? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Madrid to Syracuse.ExpandLaunch map view
  • Distance: 3,092.6 km
  • Duration: 2d 4h

What companies run services between Madrid, Spain and Syracuse, Italy?

You can take a bus from Madrid to Siracusa - Von Platen via Milano, Autostazione Lampugnano, Catania, and Catania Via Archimede in around 44h 31m.

Operators