The average bus between Mae Sai and Khon Kaen takes 23h 33m and the fastest bus takes 18h 15m. The bus service runs several times per day from Mae Sai to Khon Kaen. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Mae Sai and Khon Kaen. The earliest departure is at 9:30 AM in the morning, and the last departure from Mae Sai is at 3:00 PM which arrives into Khon Kaen at 8:45 PM. All services require a transfer at Chiang Rai and take an average of 23h 33m. The schedules shown below are for the next available departures.
Arrives next day

18h 15m • 1 change
Arrives next day

29h 45m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

29h 45m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

29h 45m • 1 change
Arrives next day

18h 15m • 1 change
Arrives next day

29h 45m • 1 change
Want to know about travelling from Mae Sai to Khon Kaen? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mae Sai to Khon Kaen. However, there are services departing from Mae Sai station and arriving at Khon Kaen station via Chiang Rai. The journey, including transfers, takes approximately 23h 33m.
Mae Sai to Khon Kaen bus services, operated by Greenbus Thailand, depart from Mae Sai station.
Mae Sai to Khon Kaen bus services, operated by Greenbus Thailand, arrive at Khon Kaen station.
Book your Mae Sai to Khon Kaen bus tickets online with Greenbus Thailand and Phetprasert Tour.
The distance between Mae Sai and Khon Kaen is 542 km. The road distance is 759 km.
You can take a vehicle from Mae Sai to Khon Kaen via Mae Sai and Chiang Rai in around 15h 50m.