Maine to Brookline Buses

Maine to Brookline buses

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Trip Overview

The average bus between Maine and Brookline takes 3h 19m and the fastest bus takes 2h 45m. The bus service runs several times per day from Maine to Brookline. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 19m
Duration: 111 mi
Distance: $35
Average price: Every 2 hours
Frequency

Bus

best

Take the bus from Portland, ME to Boston, MA - South Stationbus Portland / ...

3h 4m

$24–54

Maine to Brookline bus times

Buses run every 2 hours between Maine and Brookline. The earliest departure is at 5:33 AM in the morning, and the last departure from Maine is at 10:15 PM which arrives into Brookline at 5:51 AM. All services require a transfer at Portland, ME and take an average of 3h 19m. The schedules shown below are for the next available departures.

Departing Friday, October 9, 2026

7:42 PM → 10:37 PM
2h 55m • 2 changes
10:15 PM → 5:56 AM
Arrives next day
7h 41m • 2 changes

Departing Sunday, October 11, 2026

8:20 AM → 11:52 AM
3h 32m • 2 changes
9:20 AM → 12:58 PM
3h 38m • 2 changes
10:20 AM → 2:06 PM
3h 46m • 2 changes
11:20 AM → 2:57 PM
3h 37m • 2 changes
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Departing Monday, October 12, 2026

5:33 AM → 8:48 AM
3h 15m • 2 changes
6:50 AM → 10:04 AM
3h 14m • 2 changes
8:15 AM → 11:00 AM
2h 45m • 2 changes
8:55 AM → 11:56 AM
3h 1m • 2 changes
Show more

Departing Tuesday, October 13, 2026

5:33 AM → 8:48 AM
3h 15m • 2 changes
6:50 AM → 10:04 AM
3h 14m • 2 changes
8:15 AM → 11:00 AM
2h 45m • 2 changes
8:55 AM → 11:56 AM
3h 1m • 2 changes
Show more

Departing Wednesday, October 14, 2026

5:33 AM → 8:48 AM
3h 15m • 2 changes
6:50 AM → 10:04 AM
3h 14m • 2 changes
8:15 AM → 11:00 AM
2h 45m • 2 changes
8:55 AM → 11:56 AM
3h 1m • 2 changes
Show more

Frequently asked questions

Want to know about travelling from Maine to Brookline? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Trip Overview

Bus