Rome2Rio

Maine to Mississippi buses

Find Transport to Mississippi

View schedule
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

Trip Overview

The average bus between Maine and Mississippi takes 43h 33m and the fastest bus takes 41h 25m. There is at least one bus per day from Maine to Mississippi. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

43h 33m
Duration
1,650 mi
Distance
$331
Average price
Once daily
Frequency

Maine to Mississippi bus times

Buses run once daily between Maine and Mississippi. The earliest departure is at 2:20 PM in the afternoon, and the last departure from Maine is at 10:15 PM which arrives into Mississippi at 7:15 AM. All services require a transfer at Portland, ME and take an average of 43h 33m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

  •  → 

    Arrives +2 days

    Greater Portland Metro BusConcord Coach LinesFlixbus USAFlixbus USAGreyhound USA41h 38m • 4 changes

Departing Thursday, November 12, 2026

  •  → 

    Arrives +2 days

    Greater Portland Metro BusAmtrak ThruwayFlixbus USAFlixbus USAGreyhound USA41h 25m • 4 changes
  •  → 

    Arrives +2 days

    Greater Portland Metro BusConcord Coach LinesFlixbus USAFlixbus USAGreyhound USA41h 38m • 4 changes

Departing Friday, November 13, 2026

  •  → 

    Arrives +2 days

    Greater Portland Metro BusAmtrak ThruwayFlixbus USAFlixbus USAGreyhound USA41h 25m • 4 changes
  •  → 

    Arrives +2 days

    Greater Portland Metro BusConcord Coach LinesFlixbus USAFlixbus USAGreyhound USA41h 38m • 4 changes
  •  → 

    Arrives +3 days

    Greater Portland Metro BusAmtrak ThruwayFlixbus USAFlixbus USAGreyhound USA2d 10h • 4 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Greater Portland Metro BusAmtrak ThruwayFlixbus USAFlixbus USAGreyhound USA41h 55m • 4 changes
  •  → 

    Arrives +2 days

    Greater Portland Metro BusConcord Coach LinesFlixbus USAFlixbus USAGreyhound USA43h • 4 changes

Frequently asked questions

Want to know about travelling from Maine to Mississippi? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Maine to Mississippi.ExpandLaunch map view
  • Distance: 1,650 mi
  • Duration: 43h 33m

What companies run services between Maine, USA and Mississippi, USA?

You can take a bus from Portland Public Library to Jackson via Portland, ME, Boston, MA - South Station, Boston, New York Midtown, and Atlanta Bus Station in around 35h 29m.

Operators