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Mainz, Hauptbahnhof to Strasbourg buses

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Trip Overview

The average bus between Mainz, Hauptbahnhof and Strasbourg takes 6h 10m and the fastest bus takes 5h 4m. The bus runs, on average, 4 times per week from Mainz, Hauptbahnhof to Strasbourg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

6h 10m
Duration
246 km
Distance
€28
Average price
4 times a week
Frequency

Mainz, Hauptbahnhof to Strasbourg bus times

Buses run 4 times a week between Mainz, Hauptbahnhof and Strasbourg. The earliest departure is at 3:31 AM at night, and the last departure from Mainz, Hauptbahnhof is at 4:01 AM which arrives into Strasbourg at 1:05 PM. All services require a transfer at Frankfurt and take an average of 6h 10m. The schedules shown below are for the next available departures.

Departing Sunday, October 11, 2026

  •  → 

    DB BusFlixBus5h 4m • 1 change
  •  → 

    DB BusFlixBus5h 29m • 1 change

Departing Thursday, October 15, 2026

  •  → 

    DB BusFlixBus5h 4m • 1 change
  •  → 

    DB BusBlaBlaCar Bus9h 4m • 1 change

Frequently asked questions

Want to know about travelling from Mainz, Hauptbahnhof to Strasbourg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz, Hauptbahnhof to Strasbourg.ExpandLaunch map view
  • Distance: 246.1 km
  • Duration: 6h 10m

What companies run services between Mainz, Hauptbahnhof, Germany and Strasbourg, France?

BlaBlaCar Bus operates a bus from Frankfurt - Airport Bus Station to Strasbourg - L'Étoile Park Bus Station 4 times a day. Tickets cost €14–24 and the journey takes 3h 35m. FlixBus also services this route 5 times a day.

Operators