The average bus between Mainz and Brest takes 24h 51m and the fastest bus takes 23h 50m. There is at least one bus per day from Mainz to Brest. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run once daily between Mainz and Brest. The earliest departure is at 8:20 AM in the morning, and the last departure from Mainz is at 10:40 PM which arrives into Brest at 8:15 AM. All services require a transfer, and take on average 24h 51m. The schedules shown below are for the next available departures.
Arrives next day

23h 55m • 1 change
Arrives next day

23h 50m • 1 change
Arrives next day

23h 55m • 1 change
Arrives next day

23h 50m • 1 change
Want to know about travelling from Mainz to Brest? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mainz to Brest. However, there are services departing from Mainz station and arriving at Brest station via Paris, Quai de Bercy (Bercy Seine). The journey, including transfers, takes approximately 24h 51m.
Mainz to Brest bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Brest bus services, operated by FlixBus, arrive at Brest station.
Book your Mainz to Brest bus tickets online with FlixBus.
The distance between Mainz and Brest is 943.3 km. The road distance is 1,203 km.
You can take a bus from Mainz central train station to Brest via Paris, Quai de Bercy (Bercy Seine) in around 18h 15m.