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Mainz to Düsseldorf buses

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Trip Overview

The average bus between Mainz and Düsseldorf takes 14h 28m and the fastest bus takes 3h 58m. The bus runs, on average, 5 times per week from Mainz to Düsseldorf. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

14h 28m
Duration
221 km
Distance
€25
Average price
5 times a week
Frequency

Mainz to Düsseldorf bus times

Buses run 5 times a week between Mainz and Düsseldorf. The earliest departure is at 5:37 AM in the morning, and the last departure from Mainz is at 7:07 PM which arrives into Düsseldorf at 9:05 PM. All services require a transfer at Wiesbaden Hauptbahnhof and take an average of 14h 28m. The schedules shown below are for the next available departures.

Departing Friday, October 23, 2026

  •  → 

    DB BusFlixBus3h 58m • 1 change

Departing Saturday, October 24, 2026

  •  → 

    DB BusFlixBus16h 58m • 1 change

Departing Sunday, October 25, 2026

  •  → 

    DB BusFlixBus17h 28m • 1 change

Departing Monday, October 26, 2026

  •  → 

    DB BusFlixBus16h 58m • 1 change

Departing Tuesday, October 27, 2026

  •  → 

    DB BusFlixBus16h 58m • 1 change

Frequently asked questions

Want to know about travelling from Mainz to Düsseldorf? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz to Düsseldorf.ExpandLaunch map view
  • Distance: 221 km
  • Duration: 14h 28m

What companies run services between Mainz, Germany and Düsseldorf, Germany?

FlixBus operates a bus from Wiesbaden central train station to Düsseldorf central bus station 5 times a week. Tickets cost €18–27 and the journey takes 3h 25m.

Operators