Rome2Rio

Mainz to Düsseldorf buses

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Trip Overview

The average bus between Mainz and Düsseldorf takes 3h 56m and the fastest bus takes 3h 50m. The bus runs, on average, 5 times per week from Mainz to Düsseldorf. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

3h 56m
Duration
221 km
Distance
€26
Average price
5 times a week
Frequency

Mainz to Düsseldorf bus times

Buses run 5 times a week between Mainz and Düsseldorf. The earliest departure is at 7:07 PM in the evening, and the last departure from Mainz is at 7:15 PM which arrives into Düsseldorf at 10:05 PM. All services require a transfer at Wiesbaden Hauptbahnhof and take an average of 3h 56m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

  •  → 

    DB BusFlixBus3h 50m • 1 change

Departing Friday, November 13, 2026

  •  → 

    DB BusFlixBus3h 58m • 1 change

Departing Saturday, November 14, 2026

  •  → 

    DB BusFlixBus3h 58m • 1 change

Departing Sunday, November 15, 2026

  •  → 

    DB BusFlixBus3h 58m • 1 change

Departing Monday, November 16, 2026

  •  → 

    DB BusFlixBus3h 58m • 1 change

Frequently asked questions

Want to know about travelling from Mainz to Düsseldorf? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Mainz to Düsseldorf.ExpandLaunch map view
  • Distance: 221 km
  • Duration: 3h 56m

What companies run services between Mainz, Germany and Düsseldorf, Germany?

FlixBus operates a bus from Wiesbaden central train station to Düsseldorf central bus station 5 times a week. Tickets cost €19–28 and the journey takes 3h 25m.

Operators