- Distance: 184.7 km
- Duration: 3h 50m
The bus between Mainz and Karlsruhe takes 3h 50m. The bus runs, on average, 5 times per week from Mainz to Karlsruhe. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 5 times a week between Mainz and Karlsruhe. The service departs Mainz at 6:10 AM in the morning, which arrives into Karlsruhe at 10:00:00. All services run direct with no transfers required, and take on average 3h 50m. The schedules shown below are for the next available departures.
Want to know about travelling from Mainz to Karlsruhe? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
Yes, there is a direct bus departing from Mainz central train station and arriving at Karlsruhe central train station. Services depart five times a week, and operate every day. The journey takes approximately 3h 50m.
Mainz to Karlsruhe bus services, operated by FlixBus, depart from Mainz central train station.
Mainz to Karlsruhe bus services, operated by FlixBus, arrive at Karlsruhe central train station.
Book your Mainz to Karlsruhe bus tickets online with Omio and FlixBus.
The distance between Mainz and Karlsruhe is 108.8 km. The road distance is 137 km.
FlixBus operates a bus from Mainz central train station to Karlsruhe central train station twice daily. Tickets cost €16–25 and the journey takes 3h 50m.
