The average bus between Mainz and Salzburg takes 13h 49m and the fastest bus takes 11h 12m. The bus service runs several times per day from Mainz to Salzburg. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Mainz and Salzburg. The earliest departure is at 2:55 AM at night, and the last departure from Mainz is at 10:30 PM which arrives into Salzburg at 4:07 PM. All services require a transfer at Frankfurt central train station and take an average of 13h 49m. The schedules shown below are for the next available departures.


11h 12m • 2 changes

14h 27m • 2 changesArrives next day


12h 49m • 2 changesArrives next day


17h 37m • 2 changes

14h 27m • 2 changesArrives next day


12h 19m • 2 changesArrives next day


17h 37m • 2 changesWant to know about travelling from Mainz to Salzburg? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Mainz to Salzburg. However, there are services departing from Mainz station and arriving at Salzburg station via Salzburg South. The journey, including transfers, takes approximately 13h 49m.
Mainz to Salzburg bus services, operated by FlixBus, depart from Frankfurt central train station.
Mainz to Salzburg bus services, operated by FlixBus, arrive at Salzburg South station.
Book your Mainz to Salzburg bus tickets online with FlixBus and Salzburg Verkehr Gmbh.
The distance between Mainz and Salzburg is 424.6 km. The road distance is 584 km.
FlixBus operates a bus from Frankfurt central train station to Salzburg South 3 times a day. Tickets cost €40–65 and the journey takes 8h 5m.