The average bus between Manchester Airport (MHT) and Chicago takes 36h 25m and the fastest bus takes 32h 20m. The bus service runs several times per day from Manchester Airport (MHT) to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Manchester Airport (MHT) and Chicago. The earliest departure is at 6:05 AM in the morning, and the last departure from Manchester Airport (MHT) is at 3:35 PM which arrives into Chicago at 6:10 AM. All services require a transfer at Boston and take an average of 36h 25m. The schedules shown below are for the next available departures.
Arrives next day


31h 20m • 2 changes
Arrives +2 days


38h 35m • 2 changes
Arrives next day


31h 20m • 2 changes
Arrives +2 days


38h 35m • 2 changes
Arrives next day


31h 20m • 2 changes
Arrives +2 days


38h 35m • 2 changes
Want to know about travelling from Manchester Airport (MHT) to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester Airport (MHT) to Chicago. However, there are services departing from Manchester Airport (MHT) station and arriving at Chicago station via Boston. The journey, including transfers, takes approximately 36h 25m.
Manchester Airport (MHT) to Chicago bus services, operated by Greyhound USA, depart from Boston Manchester Airport station.
Manchester Airport (MHT) to Chicago bus services, operated by Greyhound USA, arrive at Chicago Bus Station.
Book your Manchester Airport (MHT) to Chicago bus tickets online with Greyhound USA and Flixbus USA.
The distance between Manchester Airport (MHT) and Chicago is 1,332.4 km. The road distance is 1,861 km.
You can take a bus from Boston Manchester Airport to Chicago Bus Station via Boston and New York Midtown in around 24h 38m.