Rome2Rio

Manchester to Buffalo buses

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Trip Overview

The bus between Manchester and Buffalo takes 27h 20m. There is at least one bus per day from Manchester to Buffalo. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

27h 20m
Duration
532 mi
Distance
$112
Average price
Once daily
Frequency

Manchester to Buffalo bus times

Buses run once daily between Manchester and Buffalo. The service departs Manchester at 7:15 PM in the evening, which arrives into Buffalo at 22:35:00. All services require a transfer, and take on average 27h 20m. The schedules shown below are for the next available departures.

Departing Tuesday, November 10, 2026

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    Arrives next day

    Greyhound USAGreyhound USA27h 20m • 1 change

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USA27h 20m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USA27h 20m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USA27h 20m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USA27h 20m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USA27h 20m • 1 change

Frequently asked questions

Want to know about travelling from Manchester to Buffalo? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester to Buffalo.ExpandLaunch map view
  • Distance: 532 mi
  • Duration: 27h 20m

What companies run services between Manchester, NH, USA and Buffalo, NY, USA?

You can take a bus from Manchester(Veterans Memorial Park) to Buffalo via Boston in around 12h 30m.

Operators