Rome2Rio

Manchester to Chicago buses

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Trip Overview

The bus between Manchester and Chicago takes 39h 45m. The bus runs, on average, 6 times per week from Manchester to Chicago. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

39h 45m
Duration
1,076 mi
Distance
$227
Average price
6 times a week
Frequency

Manchester to Chicago bus times

Buses run 6 times a week between Manchester and Chicago. The service departs Manchester at 7:15 PM in the evening, which arrives into Chicago at 10:00:00. All services require a transfer at Boston and take an average of 39h 45m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA39h 45m • 2 changes

Departing Thursday, November 12, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA39h 45m • 2 changes

Departing Friday, November 13, 2026

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    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA39h 45m • 2 changes

Departing Saturday, November 14, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA39h 45m • 2 changes

Departing Sunday, November 15, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA39h 45m • 2 changes

Departing Monday, November 16, 2026

  •  → 

    Arrives +2 days

    Greyhound USAGreyhound USAGreyhound USA39h 45m • 2 changes

Frequently asked questions

Want to know about travelling from Manchester to Chicago? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester to Chicago.ExpandLaunch map view
  • Distance: 1,076.1 mi
  • Duration: 39h 45m

What companies run services between Manchester, NH, USA and Chicago, IL, USA?

You can take a bus from Manchester(Veterans Memorial Park) to Chicago Bus Station via Boston and Cleveland Bus Station in around 24h 40m.

Operators