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Manchester to Des Moines buses

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Trip Overview

The bus between Manchester and Des Moines takes 2d. The bus runs, on average, 5 times per week from Manchester to Des Moines. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

2d
Duration
1,612 mi
Distance
$317
Average price
5 times a week
Frequency

Manchester to Des Moines bus times

Buses run 5 times a week between Manchester and Des Moines. The service departs Manchester at 7:15 PM in the evening, which arrives into Des Moines at 18:45:00. All services require a transfer at Boston and take an average of 2d. The schedules shown below are for the next available departures.

Departing Thursday, November 5, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USAGreyhound USA2d • 3 changes

Departing Friday, November 6, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USAGreyhound USA2d • 3 changes

Departing Saturday, November 7, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USAGreyhound USA2d • 3 changes

Departing Sunday, November 8, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USAGreyhound USA2d • 3 changes

Departing Tuesday, November 10, 2026

  •  → 

    Arrives +2 days

    Greyhound USAFlixbus USAFlixbus USAGreyhound USA2d • 3 changes

Frequently asked questions

Want to know about travelling from Manchester to Des Moines? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester to Des Moines.ExpandLaunch map view
  • Distance: 1,612.3 mi
  • Duration: 2d

What companies run services between Manchester, NH, USA and Des Moines, IA, USA?

You can take a bus from Manchester(Veterans Memorial Park) to Des Moines via Boston, New York Midtown, and Chicago Bus Station in around 37h 2m.

Operators