The average bus between Manchester and Frederick takes 17h 30m and the fastest bus takes 17h 10m. The bus service runs several times per day from Manchester to Frederick. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Manchester and Frederick. The earliest departure is at 3:20 PM in the afternoon, and the last departure from Manchester is at 7:15 PM which arrives into Frederick at 12:30 PM. All services require a transfer at Boston and take an average of 17h 30m. The schedules shown below are for the next available departures.
Arrives next day



17h 10m • 3 changes
Arrives next day



17h 15m • 3 changes
Arrives next day



17h 10m • 3 changes
Arrives next day



17h 15m • 3 changes
Arrives next day



17h 10m • 3 changes
Arrives next day



17h 15m • 3 changes
Want to know about travelling from Manchester to Frederick? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Frederick. However, there are services departing from Manchester station and arriving at Frederick station via Boston. The journey, including transfers, takes approximately 17h 30m.
Manchester to Frederick bus services, operated by Greyhound USA, depart from Manchester(Veterans Memorial Park) station.
Manchester to Frederick bus services, operated by Greyhound USA, arrive at Frederick Bus Station.
Book your Manchester to Frederick bus tickets online with Greyhound USA and BayRunner Shuttle.
The distance between Manchester and Frederick is 637.6 km. The road distance is 895 km.
You can take a bus from Manchester(Veterans Memorial Park) to Frederick Bus Station via Boston, South Station, Port Authority Bus Terminal, and Baltimore Downtown Bus Terminal, Baltimore, MD in around 12h 19m.