The average bus between Manchester and Wilkes-Barre takes 13h 16m and the fastest bus takes 9h 55m. The bus service runs several times per day from Manchester to Wilkes-Barre. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run twice daily between Manchester and Wilkes-Barre. The earliest departure is at 3:20 PM in the afternoon, and the last departure from Manchester is at 7:15 PM which arrives into Wilkes-Barre at 11:45 AM. All services require a transfer at Boston and take an average of 13h 16m. The schedules shown below are for the next available departures.
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11h 10m • 2 changes
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16h 30m • 2 changes
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11h 10m • 2 changes
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16h 30m • 2 changes
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11h 10m • 2 changes
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16h 30m • 2 changes
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11h 10m • 2 changes
Arrives next day


16h 30m • 2 changes
Arrives next day


11h 10m • 2 changes
Arrives next day


16h 30m • 2 changes
Want to know about travelling from Manchester to Wilkes-Barre? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester to Wilkes-Barre. However, there are services departing from Manchester station and arriving at Wilkes-Barre station via Boston. The journey, including transfers, takes approximately 13h 16m.
Manchester to Wilkes-Barre bus services, operated by Greyhound USA, depart from Manchester(Veterans Memorial Park) station.
Manchester to Wilkes-Barre bus services, operated by Greyhound USA, arrive at Wilkes-Barre station.
Book your Manchester to Wilkes-Barre bus tickets online with Greyhound USA, Peter Pan Bus Lines and Martz Bus.
The distance between Manchester and Wilkes-Barre is 413.6 km. The road distance is 716 km.
You can take a bus from Manchester(Veterans Memorial Park) to Wilkes-Barre via Boston, New York, and Port Authority Bus Terminal in around 11h 7m.