The average bus between Manchester Piccadilly Station and London Paddington Station takes 5h 19m and the fastest bus takes 5h 1m. The bus service runs several times per day from Manchester Piccadilly Station to London Paddington Station. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run 3 times a day between Manchester Piccadilly Station and London Paddington Station. The earliest departure is at 2:50 AM at night, and the last departure from Manchester Piccadilly Station is at 3:30 PM which arrives into London Paddington Station at 8:56 PM. All services require a transfer at Shudehill Interchange and take an average of 5h 19m. The schedules shown below are for the next available departures.
Want to know about travelling from Manchester Piccadilly Station to London Paddington Station? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester Piccadilly Station to London Paddington Station. However, there are services departing from Manchester Piccadilly Station station and arriving at London Paddington Station station via Finchley Road / O2 Centre. The journey, including transfers, takes approximately 5h 19m.
Manchester Piccadilly Station to London Paddington Station bus services, operated by FlixBus, depart from Shudehill Interchange station.
Manchester Piccadilly Station to London Paddington Station bus services, operated by FlixBus, arrive at Finchley Road / O2 Centre station.
Book your Manchester Piccadilly Station to London Paddington Station bus tickets online with FlixBus and National Express.
The distance between Manchester Piccadilly Station and London Paddington Station is 258.5 km. The road distance is 325 km.
FlixBus operates a bus from Shudehill Interchange to Finchley Road / O2 Centre hourly. Tickets cost £22–40 and the journey takes 4h 35m.