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Manchester Piccadilly Station to Middlesex buses

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Trip Overview

The average bus between Manchester Piccadilly Station and Middlesex takes 5h 18m and the fastest bus takes 4h 45m. The bus service runs several times per day from Manchester Piccadilly Station to Middlesex. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

5h 18m
Duration
188 mi
Distance
£36
Average price
Every 4 hours
Frequency

Manchester Piccadilly Station to Middlesex bus times

Buses run every 4 hours between Manchester Piccadilly Station and Middlesex. The earliest departure is at 4:40 AM at night, and the last departure from Manchester Piccadilly Station is at 11:40 PM which arrives into Middlesex at 6:55 AM. All services require a transfer at Manchester Central Coach Station and take an average of 5h 18m. The schedules shown below are for the next available departures.

Departing Sunday, October 18, 2026

  •  → 

    National ExpressFirst Bus London5h 6m • 1 change
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    National ExpressMetroline Travel5h 13m • 1 change
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    National ExpressMetroline Travel5h 2m • 1 change
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    National ExpressFirst Bus London4h 54m • 1 change
  • Show more

Departing Monday, October 19, 2026

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    National ExpressFirst Bus London5h 5m • 1 change
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    National ExpressMetroline Travel4h 51m • 1 change
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    Arrives next day

    National ExpressMetroline Travel7h 19m • 1 change

Departing Tuesday, October 20, 2026

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    National ExpressFirst Bus London5h 5m • 1 change
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    National ExpressMetroline Travel4h 51m • 1 change
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    Arrives next day

    National ExpressMetroline Travel7h 19m • 1 change

Departing Wednesday, October 21, 2026

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    National ExpressFirst Bus London5h 5m • 1 change
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    National ExpressMetroline Travel4h 51m • 1 change
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    Arrives next day

    National ExpressMetroline Travel7h 19m • 1 change

Departing Thursday, October 22, 2026

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    National ExpressFirst Bus London5h 5m • 1 change
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    National ExpressMetroline Travel4h 51m • 1 change
  •  → 

    Arrives next day

    National ExpressMetroline Travel7h 19m • 1 change

Departing Friday, October 23, 2026

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    National ExpressFirst Bus London5h 14m • 1 change
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    National ExpressMetroline Travel5h 17m • 1 change
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    National ExpressMetroline Travel5h 8m • 1 change
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    National ExpressMetroline Travel5h 8m • 1 change
  • Show more

Departing Saturday, October 24, 2026

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    National ExpressMetroline Travel4h 45m • 1 change
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    National ExpressMetroline Travel4h 58m • 1 change
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    National ExpressMetroline Travel4h 59m • 1 change
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    National ExpressMetroline Travel5h 4m • 1 change
  • Show more

Frequently asked questions

Want to know about travelling from Manchester Piccadilly Station to Middlesex? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester Piccadilly Station to Middlesex.ExpandLaunch map view
  • Distance: 188.3 mi
  • Duration: 5h 18m

What companies run services between Manchester Piccadilly Station, England and Middlesex, England?

National Express operates a bus from Manchester Central Coach Station to Golders Green Station every 2 hours. Tickets cost £28–50 and the journey takes 4h 10m.

Operators