The average bus between Manchester Piccadilly Station and Milton Keynes takes 3h 52m and the fastest bus takes 3h 9m. There is a bus service every few hours from Manchester Piccadilly Station to Milton Keynes. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.
Buses run hourly between Manchester Piccadilly Station and Milton Keynes. The earliest departure is at 2:45 AM at night, and the last departure from Manchester Piccadilly Station is at 11:40 PM which arrives into Milton Keynes at 6:49 AM. All services require a transfer at Manchester Central Coach Station and take an average of 3h 52m. The schedules shown below are for the next available departures.

3h 29m • 1 change

4h 29m • 1 change

3h 19m • 1 change

4h 24m • 1 change

4h 14m • 1 change

3h 19m • 1 change

4h 19m • 1 change

3h 44m • 1 change

4h 15m • 1 change

3h 9m • 1 change

3h 20m • 1 change

4h 15m • 1 change

4h 31m • 1 change

3h 38m • 1 change

3h 50m • 1 change

4h • 1 change
Want to know about travelling from Manchester Piccadilly Station to Milton Keynes? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.
No, there is no direct bus from Manchester Piccadilly Station to Milton Keynes. However, there are services departing from Manchester Piccadilly Station station and arriving at Milton Keynes station via Milton Keynes Coachway. The journey, including transfers, takes approximately 3h 52m.
Manchester Piccadilly Station to Milton Keynes bus services, operated by National Express, depart from Manchester Central Coach Station.
Manchester Piccadilly Station to Milton Keynes bus services, operated by National Express, arrive at Milton Keynes Coachway station.
The distance between Manchester Piccadilly Station and Milton Keynes is 188 km. The road distance is 249 km.
National Express operates a bus from Manchester Central Coach Station to Milton Keynes Coachway every 30 minutes. Tickets cost £29–70 and the journey takes 4h.