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Manchester to Indianapolis buses

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Trip Overview

The average bus between Manchester and Indianapolis takes 8h 5m and the fastest bus takes 8h. The bus service runs several times per day from Manchester to Indianapolis. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

8h 5m
Duration
353 mi
Distance
$75
Average price
Twice daily
Frequency

Manchester to Indianapolis bus times

Buses run twice daily between Manchester and Indianapolis. The earliest departure is at 12:20 AM at night, and the last departure from Manchester is at 3:10 AM which arrives into Indianapolis at 12:10 PM. All services run direct with no transfers required, and take on average 8h 5m. The schedules shown below are for the next available departures.

Departing Tuesday, November 3, 2026

  •  → 

    bus bus 8h • Direct

Departing Wednesday, November 4, 2026

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    bus bus 8h 10m • Direct
  •  → 

    bus bus 8h • Direct

Departing Thursday, November 5, 2026

  •  → 

    bus bus 8h 10m • Direct
  •  → 

    bus bus 8h • Direct

Departing Friday, November 6, 2026

  •  → 

    bus bus 8h 10m • Direct
  •  → 

    bus bus 8h • Direct

Departing Saturday, November 7, 2026

  •  → 

    bus bus 8h 10m • Direct
  •  → 

    bus bus 8h • Direct

Departing Sunday, November 8, 2026

  •  → 

    bus bus 8h 10m • Direct
  •  → 

    bus bus 8h • Direct

Departing Monday, November 9, 2026

  •  → 

    bus bus 8h 10m • Direct
  •  → 

    bus bus 8h • Direct

Frequently asked questions

Want to know about travelling from Manchester to Indianapolis? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester to Indianapolis.ExpandLaunch map view
  • Distance: 352.7 mi
  • Duration: 8h 5m

What companies run services between Manchester, TN, USA and Indianapolis, IN, USA?

Greyhound USA operates a bus from Manchester to Indianapolis Union Station twice daily. Tickets cost $65–100 and the journey takes 8h 10m.

Operators