Rome2Rio

Manchester to Pittsburgh buses

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Trip Overview

The bus between Manchester and Pittsburgh takes 21h 20m. There is at least one bus per day from Manchester to Pittsburgh. The journey time may be longer on weekends and holidays; use the search form on this page to search for a specific travel date.

21h 20m
Duration
654 mi
Distance
$141
Average price
Once daily
Frequency

Manchester to Pittsburgh bus times

Buses run once daily between Manchester and Pittsburgh. The service departs Manchester at 7:20 PM in the evening, which arrives into Pittsburgh at 17:40:00. All services require a transfer, and take on average 21h 20m. The schedules shown below are for the next available departures.

Departing Wednesday, November 11, 2026

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    Arrives next day

    Greyhound USAGreyhound USA21h 20m • 1 change

Departing Thursday, November 12, 2026

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    Arrives next day

    Greyhound USAGreyhound USA21h 20m • 1 change

Departing Friday, November 13, 2026

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    Arrives next day

    Greyhound USAGreyhound USA21h 20m • 1 change

Departing Saturday, November 14, 2026

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    Arrives next day

    Greyhound USAGreyhound USA21h 20m • 1 change

Departing Sunday, November 15, 2026

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    Arrives next day

    Greyhound USAGreyhound USA21h 20m • 1 change

Departing Monday, November 16, 2026

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    Arrives next day

    Greyhound USAGreyhound USA21h 20m • 1 change

Frequently asked questions

Want to know about travelling from Manchester to Pittsburgh? We have put together a list of the most frequently asked questions from our users such as: What is the cheapest mode of transport? What is the quickest option? How much do tickets usually cost? and many more.

Map of how to get from Manchester to Pittsburgh.ExpandLaunch map view
  • Distance: 654 mi
  • Duration: 21h 20m

What companies run services between Manchester, TN, USA and Pittsburgh, PA, USA?

You can take a bus from Manchester to Pittsburgh Intermodal Station via Columbus in around 16h 5m.

Operators